Facts about the skin and its importance. Nourishing the Skin from the Inside Out. Nutrition of natural products in natural supplements to compliment the skin.

Skin is the largest organ of the human body, with a total surface area between 1.5 to 2m2!

Each cubic centimeter of skin is home to approximately one million bacteria. Maintaining microbial balance is therefore crucial not only for healthy skin, but also for overall wellbeing, as it provides local defense against invading organisms and keeps the immune system primed and ready for action.2

The skin is a representative of the health and wellbeing of your internal body. If the internal body is suffering, so it manifests on the skin. The eyes are not the only windows to your soul!

The two components of corneum and corneocytes work together in maintaining skin function. Corneocytes not only provide physical structure, but also produce natural moisturizing factors (NMFs) which attract and retain water in the stratum corneum. Where there is damage to the lipid-rich extracellular domain (i.e. from excessive exposure to irritants like soapy water and detergents or the use of topical corticosteroids), these NMFs may be leached from the corneocyte, compromising the hydration capacity of the skin. The resultant transcutaneous water loss actually impedes the activity of desquamatory enzymes in the stratum corneum which are responsible for proper skin shedding, ultimately leaving the skin dry and flaky.5

Compromise the ability of these lipids to impede microbial growth, leaving the skin even more susceptible to pathogenic insult and subsequent infection.

References

Hun Lee S, KyooJeong S, Ku Ahn S. An update of the defensive barrier functions of skin. Yonsei Med J. 2006;47(3):293-306.

Prasad AS. Clinical, immunological, anti-inflammatory and antioxidant roles of zinc. ExpGerentol. 2008; 43(5):370-7.

Lansdown ABG, et al. Zinc in wound healing: Theoretical, experimental, and clinical aspects. Wound Rep Reg. 2007; 15:2-16.

Hon KL, et al. Serum levels of heavy metals in childhood eczema and skin diseases: Friends or foes. Pediatr Allergy Immunol. 2010; 21:831-6

Bikle DD, Chang S, Crumrine D, Elalieh H, et al. 25 hydroxyvitamin D 1 α-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis. J Invest Dermatol. 2004; 122:984-992.